Large plumes of thick smoke can be seen over Wigan after another fire broke out at a derelict mill.
The fire service received 10 calls in 10 minutes, starting shortly before 11am today, alerting them to the blaze at the Pagefield building.
A large amount of rubbish had been set alight in the mill.
Three fire engines have attended - two from Wigan and one from Bolton Central fire station.
A fire service spokesman said firefighters were continuing to tackle the blaze, some wearing breathing apparatus.
It is the second time in five days that firefighters have been called to the abandoned site, after timber was set alight there on Monday evening.
The former college building has been the site of a series of fires in recent years.
The Evening Post revealed earlier this month that firefighters have been called to no fewer than 24 occasions since 2009.
A blaze suspected to have been started by a youth gang in March last year was by far the most serious and was attended by 18 fire engines.
Several warnings have been issued about the dangers of entering the abandoned building off Mesnes Park.
Tony Callaghan, watch manager at Wigan fire station, said earlier this week: “We are just waiting for somebody to get seriously injured in there.”