PIVOTAL Blake Green could be missing for six weeks with an ankle problem.
Scans revealed the extent of the injury and coach Shaun Wane is resigned to being without the Australian for a “five to six week” spell.
Scrum-half Matt Smith is also likely to be absent for another three weeks with a shoulder injury suffered the previous week.
And having toyed with the idea of moving either Sean O’Loughlin or Sam Tomkins into the halfback roles for Saturday’s trip to London, Wane says he is now leaning towards playing both Sam Powell and George Williams.
The only first-team appearance made by Williams was in a 60-10 Challenge Cup win against Leigh.
“I’m happy with Sam and George and I’m excited to see them play. That’s their opportunity,” said Wane.
“This is another challenge for us. That’s why I include the kids in training so much, for times like this. They’re in, I don’t want to be moving the squad around.
“I did a bit of that on Sunday at Hull KR as it was unexpected but this week I start with my stand-off and scrum-half as normal.
“Periods like this don’t overly disappoint me as I’m genuinely looking forward to seeing how Sam and George do. There’s a lot of responsibility on them but they train to our standard and intensity, so I don’t expect a dip.”
Chris Tuson, Gil Dudson and Jack Hughes are all doubtful for Saturday’s match.
THE draw for the Challenge Cup quarter-finals will take place this Saturday, between 7am and 9am, on BBC Breakfast TV.