James Moorcroft and Rhiannon Dixon split from Blundell's Gym
Both climbed through the ranks to turn professional under the guidance of former IBF Intercontinental champion Lee Blundell and his son Luke, who also coaches at the Stephens Way-based gym.
The development may surprise fans, given the lavish praise both boxers have given their coaches in recent times.
It is unclear where they will move to.
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Hide AdBlundell said: “They have decided to go their separate ways, we’ve had a lot of good times together and I wish them all the best. But we have to move on.
“We have an abundance of talent coming through behind them and I can’t wait to see them develop.
“Joe Howarth is hoping to make his professional debut in November and there are others ready to take the next step – with a lot of talent behind them in the juniors, too.”
Moorcroft, 27, made his professional debut in April 2017 and has won 13 of his 14 fights.
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Hide AdDixon, who also works full-time as a pharmacist, has won her two opening bouts since turning professional last September.
The 24-year-old, who took up the sport to get in shape, is ranked fourth best lightweight in Great Britain.