WIGAN let a 20-6 lead slip from their grasp as they fell to their first defeat of the new Super League campaign.
A week after a dramatic defeat to Brisbane in the World Club Series, they were again made to pay for their ill-discipline and handling mistakes.
From the 41st minute, Wigan failed to get over the Robins’ line.
And the home side made them pay with three unanswered tries through off-season recruits Ken Sio, Mitch Allgood and Keiran Dixon to snatch the win.
In a dramatic final few minutes, the Warriors tried to conjure a match-winning try, but all attempts fizzled out.
Earlier, they had appeared well on course for victory when they scored three tries in a five-minute period to take a 14-point lead.
Lee Mossop crowned his first appearance for Wigan in 18 months with a try. Touchdowns by Josh Charnley and George Williams sandwiched the half-time break to give Wigan a 20-6 advantage.
But they relapsed into the erratic, error-strewn form which had blighted their opening half-an-hour.
Joe Burgess was guilty of allowing Sio to pounce on a ball in the in-goal area for the game’s opener, though he made amends with a try himself in the 27th minute.
Hull KR: Cockayne; Mantellato, Salter, Goulding, Sio; Campese, Kelly; Walker, Boudebza, Allgood, Blair, McCarthy, Burke. Subs: Larroyer, Green, Horne, Dixon.
Wigan: Hampshire; Charnley, Gelling, J Tomkins, Burgess; Williams, Smith; Sutton, McIlorum, Tautai, C Farrell, L Farrell, Bateman. Subs: Clubb, Patrick, Mossop, Powell.
Referee: Robert Hicks