Shaun Wane has named his squad for the trip to Leeds with three frontline players returning from injury.
As revealed earlier this week, prop Ryan Sutton, forward Liam Farrell and centre Oliver Gildart are set to return from spells on the sidelines.
They replace Joe Bretherton, Callum Field and Josh Ganson in the initial 19-man squad.
Gildart has been missing for four weeks following a shoulder injury, Sutton hasn’t played since the win over Leigh owing to an eye problem and Farrell has missed Wigan’s last two outings following a calf injury.
Anthony Gelling and Ben Flower both left the action early against Hull but have been given the green light to play.
If everyone is fot to play, centre Liam Forsyth would appear an obvious candidate to be omitted when the squad is trimmed by two on Friday, with Nick Gregson or Frenchman Romain Navarrete the other.
Leeds welcome back Brett Delaney but are still without injured Keith Galloway and Stevie Ward, and banned Brad Singleton. Kick-off at Headingley is 8pm and the game is live on Sky Sports.
Warriors 19-Man squad: Tony Clubb, Tom Davies, Morgan Escaré, Liam Farrell, Ben Flower, Liam Forsyth, Anthony Gelling, Oliver Gildart, Nick Gregson, Willie Isa, Thomas Leuluai, Liam Marshall, Romain Navarrete, Frank-Paul Nuuausala, Sam Powell, Ryan Sutton, Taulima Tautai, Joel Tomkins & George Williams.