Shaun Wane has not ruled out bringing in reinforcements to cover for the injured Micky McIlorum.
But the Warriors boss insists there is “no panic” to make a signing, either on loan or permanently.
It comes as Leigh owner Derek Beaumont has denied Wigan are chasing Centurions hooker Bob Beswick.
Ex-Warriors player Beswick had been linked with a move to his home-town club.
Sam Powell is set to be promoted from the bench, but Wane’s back-up options have been restricted by injuries to reserve players Luke Waterworth and Jake Shorrocks.
Wane said: “If we’ve someone available we will have a look.
“If I can bring someone in who can make us better I will do that. But there’s no panic. I’m gutted for Micky, but I’m not stressed.
“I’ve got Kyle Shelford, Josh Ganson - Luke is injured at the moment - but we have players who can go there.”
Forward Nick Gregson is one of those options and he has been included in Wigan’s 19-man squad.
Sean O’Loughlin has also played there.
Either way, Wane knows his team must collectively raise their game to cover for the loss of McIlorum’s defensive grit.
“It’s a challenge for the team to pick up the slack,” he said.
“Sam defends tough, he hasn’t go quite the mongrel in his game but he will get it.”
Prop Lee Mossop and untested Nick Gregson and Joe Bretherton have replaced injured McIlorum, Willie Isa and Josh Charnley in Wigan’s 19-man squad.
Wigan’s 19-man squad: Bateman, Bretherton, Burke, Clubb, Farrell, Flower, Gelling, Gildart, Gregson, Manfredi, Mossop, O’Loughlin, Powell, Sarginson, Smith, Sutton, Tautai, Tierney, Williams
Salford’s 19-man squad: Carney, Dobson, Evalds, Flanagan, Griffin, Griffin, Johnson, Jones, Kopzcak, Krasniqi, Lannon, Lee, Lui, Murdoch-Masila, O’Brien, Sarsfield, Sa’u, Tomkins, Walne