Jackson Hastings to play full-back for Wigan Warriors
Oliver Gildart and Liam Marshall return for their first games of the year but Dom Mandredi (knee) and Morgan Smithies miss out with minor injuries.
Kick-off is 7.45pm and this is the first game fans have been allowed into the DW Stadium in 15 months.
Wigan: Hastings; Bibby, Isa, Gildart, Marshall; Leuluai, Smith; Singleton, Powell, Bullock, Bateman, Farrell, Partington. Subs: Byrne, Havard, Shorrocks, Pearce-Paul.
Hull KR: Quinlan; Crooks, Minikin, Kenny-Dowall, Hall; Takairangi, Lewis; Maher, Parcell, Lawler, Johnson, Linnett, Hadley. Subs: Vete, Litten, King, Storton.